Argatroban Half Life at Life

Argatroban Half Life. There are no specific guidelines for dosing in The main route of argatroban metabolism is hydroxylation and aromatization of the 3 methyltetrahydroquinoline ring in the liver.

Upon discontinuation of the administration of the drug, anticoagulant effect should disappear completely within 12 hours in most patients, although longer anticoagulant effects have been described. The main route of argatroban metabolism is hydroxylation and aromatization of the 3 methyltetrahydroquinoline ring in the liver. The aptt is used to monitor its anticoagulant effect, and the dose is adjusted to achieve an aptt 1.5 to 3 times the baseline value but not to exceed 100 seconds.

Specific Anticoagulant and Antiplatelet Agent Reversal

The aptt is used to monitor its anticoagulant effect, and the dose is adjusted to achieve an aptt 1.5 to 3 times the baseline value but not to exceed 100 seconds. The apparent terminal elimination half life (mean ± sd) is 52 ± 16 min. Clearance (mean ± sd) was 5.2 ± 1.3 ml/kg/min. The main route of argatroban metabolism is hydroxylation and aromatization of the 3 methyltetrahydroquinoline ring in the liver.