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Half Life Definition Pharmacology. It is the time in which the total amount of drug within the body, after equilibrium of plasma with other compartment (fat/muscle), falls by one half or 50%. (t 1/2), the time required to decrease the amount of drug in body by 1/2 during elimination (or during a constant infusion).
Factors affecting parameters from www.slideshare.net
The amount of time it takes for the concentration of that medication in the patient's blood to be reduced by one half. It also indicates whether accumulation of the drug will occur under a multiple dosage regimen and it. It is the time in which the total amount of drug within the body, after equilibrium of plasma with other compartment (fat/muscle), falls by one half or 50%.
Factors affecting parameters
(t 1/2), the time required to decrease the amount of drug in body by 1/2 during elimination (or during a constant infusion). Beta half life = tissue / elimination half life. It is the time in which the total amount of drug within the body, after equilibrium of plasma with other compartment (fat/muscle), falls by one half or 50%. It is the time in which the pharmacological effect of the drug and its active metabolites falls by one half or 50%.
